Ligand-targeted toxins (LTTs) are bioengineered molecules which Saddle Carriers are composed of a targeting component linked to a toxin that induces cell death once the LTT binds its target.Bispecific targeting allows for the simultaneous targeting of two receptors.In this review, we mostly focus on the epidermal growth factor receptor (EGFR) as a
Abstract Long-persistent luminescence (LPL) materials have applications from safety Accessories signage to bioimaging; however, existing organic LPL (OLPL) systems do not align with human scotopic vision, which is sensitive to blue light.We present a strategy to blueshift the emissions in binary OLPL systems by upconverting the charge-transfer (CT)
We discuss specific challenges and solutions in infant MEG, which is one of the most technically challenging areas of MEG studies.Our results can be Saddle Carriers generalized to a variety of challenging scenarios for MEG data acquisition, including clinical settings.We cover a wide range of steps in pre-processing, including movement compensation
We have shown that the flow velocity of Shirase Glacier can be estimated by applying the offset tracking method to the amplitude images derived from the phased array type L-band synthetic aperture radar type-2 (PALSAR-2) onboard the Advanced Land Observing Satellite-2.Although the offset tracking is widely used, the method is sometimes not applicab
Usucapio (acquisitive prescription or adverse possession) ultimately brings the factual and legal situation in accord by "turning" a long-term possession that was incompatible with ownership into legal ownership (title to property).The former owner loses the right of ownership whereas the possessor becomes the new owner, thus acquiring the right of